New Cancer Research Projects Are Stirring Lively Interest

-room.”

the tumor cell is strange—but proving it_is another matter. The cancer cell is a normal cell running wild Perhaps it is like a normal.cell that s

The scientific ‘assault on cancer has been long, in- tense and frustrating. , «\ final breakthrough is not yet in sight. But several new enough Yesearch reports, taking a it doesn't awaken ‘similar tack, are stirring fence mechanisms. lively interest. This is the Or perhaps some cancer cells ‘first of two articles on the have a way of subduing the ‘atest developments and body's defence mechanisms. their implications. Often a cancer patient dies of ‘ pneumonis or other infection— ' By JOHN BARBOUR his body's resistance s6 lowered NEW YORK (AP)—The effort |that he can’t fight back. t: enlist the body's own de-| Still, there are a few cases fénces against an invading dis-|where cancers in humans sud- ease is perhaps the most active |denly and mysteriously shrink front today in the battle against and disappear. cancer. A scattering of research, And there are cases, when reports has focussed fresh in- the main or primary tumor is terest on this approdch removed by surgery or de- One expert calls it ‘the’ most /stroyed -by radiation, in which promising area of cancer ré- seed cancers spread from the | search today.’’ Another, looking main tumor.unaccountably. at recent experiments, finds! Or there are situations where | there’s ‘‘a ray of light in a dark seed cancers suddenly appear | a at other places in the body, long | If there is some-hope—that-re-afterthe— primary ~tumor~has |

_gearchers-may.he.working on-ibeen-_removed. That, in itself,

i

some promising leads, it must might suggest that the body's be set against the background /defence mechanism held _ the of ‘a thousand disappointments |seed cancers in check for some™ of the past. tim.

In the last months there have | AS PLAYED SOME Ri OLE

. been” some interesting varia~ "7 the h. tions onthe idea that in the | #il these—cases,research-— dmmune processes of _ living |S believe, the body's immune

'rtechanis mhas played a role, | the

-ereatures there is a way to de- feat cancer, just as virusse and bacteria are defeated.

jrecognizing and _ fighting

‘cancer as.an intruder. ©

_| Using immunity against dis- lease is hardly new. By the time |

SOME DISAGREEMENT most Canadian and United

There are a number of cur-

rent reports—but researchers States children are 5, they have disagree on their ultimate |been immunized against small- | value: ‘pox, polio and diptheria. |

In Detroit, researchers claim | The procedures

to have created an experimental

method linking) human tumor |live, but. weakened, polio virus. |

~gntigens:————-

But the proof is difficult, and recent attempts to show the ‘same holds true for human tum-

ors are being’ anxiously fol- | \lowed. = : |A NEW TACT |

| The proof that antibodies can jbe stimulated by cancer cells is, \fairly new. In 1953, researchers ‘found they could make a mouse immune to a chemically-induced ‘tumor by first transplanting a itumor from a_ related mouse, then surgically removing it. The ‘mouse’ exposed to the tumor

transplant for a period was then resistant to further _ at- tempts to transplant that same kind of tumor.

Other researchers have

learned to —play_—tricks—with-

antigens in animals—and stimu- late antibodies against cancer.

For instance,.one virus was known to cause leukemia in the newborn of a certain inbred family of white mice. A, few months after inoculation the baby ‘white—mice—developed—leu- kemia. Adult’ white mice of the same family could then be given the leukemia by injecting them with leukemic cells from the newborn mice.

The same virus could be used to. produce leukemia in a dif- ferent mouse family—a black mouse. But when leukemic cells from the black mice were in-

are many. ected into adult white mice, | \The: human may be given & the white mice rejected them |

because their immunity sys-

Retail

~~~ @ells--to~ rabbit--protein--to—prod jHe responds -by-producing.antl-tms ..-recognized...the black! , rarmer-owned- retail org

ae

~—tearchers—have—produced—tab-—|mechanism—-reeognizes——“‘virus.

bodies — disease - fighting agents—against the virus. Even when he encounters more viru- | lent polio viruses, the’ antibod-.'

@ cancer patient's body into fighting his own cancer. But they say their work is strictly

preliminary and needs more , 4 s laboratory confirmation and re-|ies are effective against it. | finement. Sometimes, instead of live vir-|

uses, killed viruses or live but}

Y., researchers related viruses can be used to|

In Buffalo, -N.

ently other disease-fighters di- | rectly associated with cells. | Lymphocytes—a type of white) blood cell—carry disease-fight- | ing equipment. The body even | has some specialized cells that actually devour some foreign

of Philadelphia, -involved in an experimental transplant’ died Monday. A spokesman in Buf- ‘falo said the transplant.was of li or no value in Mr. Grif- fith'S “case. :

His partner in the experiment, Robert F..Allen of Tucson, Ariz., and two other men who took part in a stmitar experl- ment were reported to be pro- gressing, but the hospital said it would be some time before.

ARE PROTEIN MATTER “Antibodies themselves are) specially designed bits of pro- | tein which can fit onto foreign’) protein, neutralizing it.

\matter that invades. . iby

mouse leukemic cells as for- eign, coming from mice that were genetically different.

PRODUCED NOTHING

Weeks later, the researchers took the same white mice tha’ had rejected the black mice.

ulated the white ‘mice to pro-

\duce: defences against such cells

and those defences were effec- tive against leukemic cells from their own family.

These experiments suggested that tumors might be dealt with b: immunological techniques. But the question - persists:

Can- you demoristrate-that—hu-|:

man tumors also are identified by the body as foreign intrud- ers? Do they also possess an- tigens that would stimula ttehe

ization, Agro Co-op Associated Limited will be opened officially ithis afternoon by Premier Wal- lter Shaw. The location is on Ex- lhibition Drive, and the manager

to about “It’s surprising problems-can be handled by the computer in around five min- utes for a cost of about $45 or $50,”. Monte..Hickenlooper,..mar- keting manager of the firm,

: evalu. Foreign material that stimu- -

Grr condition would be aren aie polices production "is body to produce antibodies . Many of them od : icalled an antigen. - aga. cancer? > | specialists forest produc

HAVE USED RABBITS "in the case of viruses, for in-| Is there something in com- | mining, acturing and

In Los Angeles some fre-istance, the body's immune

bits they believe to be tolerant particle by antigens in its pro- |

——ef—allhumantissue—and “have ttective protein coat—and-forms- _ talked about using the -rabbits |

antibodies to lock the virus in

|

go between various kinds of

body’s defences? Or - is each

tumor different?

search for the answers !s | pune!

to manufacture anti - cancer /its: coat and prevent it from in-|under way. nail * ¢om- : serum for ‘human- patients. But Ifecting a i ee | (Next: Tentative human tests) /'T@ a precio aoe ian w other scientists -have questions | within a few minutes the

to asi about the method. U S Fi P hi ‘Rental answer is tapped out on a

_ Although these reports have | : : printer branch office <

ridden the crest of the recent | ndoacta irm US Ing Pa as lines a :

ews, there have been countless |

tall sdvencer ia" wettmamnee- Of Computer_in Vancouver

transplant operations. The body /for the Js able to recognize the strange- | — o something seers | to # and to mobilize defences nuclear reactor pgainst the intrnder—except for, [See men e the contract, | perhaps, the cancer cell. - | and because there is inshfficient | HARD TO PROVE U.S. government work to oper- | ‘ It has mof been shown, in the | ate the giant computer at {ull

Hanford project a equare-mile atomic cen- tre and site of the world’s larg- |

eyes of most researchers, that | capacity, the Los Angeles com- |

the human tumor cells harbor | pany is committed to making | foreign characteristics: that will | the computer available to pri- enable the body to recognize | vate industry.

them as enemies. Most believe

‘ . ‘ a ‘ ‘

i ‘

Along Saskatchewan Border

; REGINA CP) — Bumper! ‘In the past, many farmers

grain crops and new federal |in the southern extreme of our,

‘loan procedures mean more| province were hampered be- Saskatchewan farm land will be!cause of the lack of cash and owned by Canadians. provincia] | procedural difficulties in obtain- ‘agriculture officials forecast. {ing loans. The good crops of ; American land_ purchases the .last three years and im- gear the US border continued proved loaning procedures by ‘to rise in the 1962-64 period but | federal agencies have tended to ‘then fell off in the face of com- | give Saskatchewan farmers just -petition, from Canadian farmers as much opportunity to pur- ‘with new-found money. chase the land as: Americans.”

Agriculture Minister Doug As well as difficulty in ob: |

«McFarlane said the trend will | taining loans and having litfle |

‘continue, bringing an end to re-'cash bargaining power, some ‘sentment which farmers har- Saskatchewan farmers were bored against Americans whojperhaps over cautious, Mr could beat them at the auction ' Brown. suggests. But this wasn't block. one - likely to ‘continue.

Americans own 2.1 per cent, One factor which attracted of the land in a surveyed strip | American buyers to the Sas- ‘54 ‘miles ‘dgep by 320 miles |katchewan grain lands was the broad along the Saskatchewan lower price, Mr. Brown said ‘border. Provincia). government ‘‘For example, land selling for surveys have not eovered areas | $40 to $45 an acre in the frontier further north. _|and Climax areas (of south.

J A. Brown, director of agri- western Saskatchewan) is sim- eultural economics and statis- ilar to Jand selling in Montana tics, said the survey showed for $90 to $100 an acre" ‘most American owners in the Mr. Brown 4aid the survey ‘area ‘‘farm from across the |indicated American buyers were line ’’ Farther north, more rent paying as much as three to five ‘the land to Canadians times the assessed value of:

From March 31, 1982, to Dee. farm Jand after ‘‘considerable

Offices have been opened |

Canadian Farmers Buy More |

's--that. would awaken the | _

t |and directors are holding open | |house through the afternoon and |

+ i how . many |

id in an interview Wednes. |

Mr. Smith shows a product to a customer

etail Organization Holding Open House

sent,=-will-be-served-to visitors. -

This organization is owned by 75 Queens County farmers, man- ager Donald Smith told this pa- per last evening. . Actually.,the organization has been underway since February of last year, but it moved to its new location,

have exchanged small _trans- ; : : : : leukemia cells ‘and injected evening. . built especially for this business, Baia i he Wehat each a Ss lhtem with leukemia cells from Coffee and doughnuts, the pop- ja little more than a month ago. would develop usable defences GEN NEW CANCER. . _|white mice. Normally, these jular refreshments of the ~ Ez = ae ah 18 members Sgainst the tumor of the other.| ‘The body has;a spectrum of leukemia cells would have pro-|chase or leaes UaMipmNES, tet jin Nowe just about ev However, they have maintained |disease-fighting agents. Anti iduced leukemia in the white . no ci s about e oy silence onthe: final outcome.:of bodies flow freely in the blood mice—but they didn’t. charge. A businessman pays |kind of farm equipment. ‘Wha “th experiment. 9° ‘\stream, produced’ by certain’ Receiving the geneticatly dif only: for- Weed ee ae oe atl far eon . One patient, Harry T. Griffith |cells. Then there are appar- iferent leukemia cells had stim- comnpane Se ¢ oe other ing Hae E - hos an goods”,

BULK STATION

It is‘a bulk station for live- stock feeds. ‘‘We bring in pellet- ed feed in bulk carloads ... We'll have custom mixing and milling facilities later’, Mr. Smith said. The equipment for this is now on the way, he added. = annual meeting a few

Best of Luck

a

|

| |

}

weeks ago revealed a gross turn- over of a quarter million dollars. during the year, it was learned. A patronage divident of two and | one-half percent was paid to) shareholders. ; ’ Items carried include ‘such ‘farm equipment as stable equip- ment, garden tools, chemical | sprays and equipment, a com- | plete stock of forage and grain ‘crop seeds, work clothing and | footwear, dairy - supplies —and. many other items. i

manager, is a graduate of Nova | Scotia Agricultural College and | of MacDonald College, Ste Anne de Bellevue, Quebec. BACKGROUND

Mr. Smith’s background, after graduation covers working for Maritime Co-op Services in Southern New Brunswick and P.E.I. on technical services .in ‘the company’s feed department. _.He_was transferred to Kent-_ Vville, N.S. “when MCA opened ithe most modern feed mill in the | Maritime area’. He was trans- ferred to Charlottetown in Octo- ber 1964 as manager of the or- | ganization here. j ~Mr. Smith works for MCS | which has .a’“manager provision | arrangement with the local | icompany. Don is a son of Harold | |Smith, MLA Pownall.

‘| Management & Staff ie

minute |We were pleased to have been connected with the construction of this new building.

Is Studied

[ovine in the U.S., Prime Mints-

field because the US draft laws applied to Canadians in

| register for selective service

Mr. Smith who is the plant | —

and Mrs. Smith of}

18 The Guardian, Charlottetown, Thur., April 28, 1968,

U.S. Draft — Legislation

MANY TOUR NORTH

ft 1 Norwegian youth hostels » Mrs Briscoe said her famuy | eer. ta put | lived in the U.S. only a year up travellers ’ over.

jand that her son is not, an night visits in 1965, 57 per cen: ‘American citizen. : of *them foreigners.

ay Best Wishes AgeCosp

Canadians spending one or two/|- ° jyears in the U.S who are con- | 6 d On 3 ices — sa oo '

sidered subject to’ the. draft | | there. : | said the |

|should’ have asked the RCMP

| to accompariy him *

OTTAWA (CP)—The govern-, ment is studying United States | military draft legislation and the status of Canadian citizens

ter Pearson has told- the Com- | mons. New Democratic

Leader

‘question involves an interpreta- |tion of’ the U.S. law. | | He said Canada has had a good deal of experience- in this

The prime minister

te

the U.S. World War. | The subject arose over a} Vancouver incident last month when “FBI agent Alfie Gunn visited a suburban home to ask questions of Glen Briscoe. --His mother said the agent implied the-youth would be arrested for | _alleged evasion of _U.S.._ laws |--# i all 18-Vear-olds to

during the Second |

Solicitor-General Pennell said ‘Monday the FBI-man~~ had no 7; authority to ) enter the home and

%

~The makers of IOSAN, Canada’s most widely-used “Tamed Todine” Cleaner/Sanitizer for 5): dairy farms, salute AGRO

» ~~ CO-OP LIMITED, on the opening of their new farm service centre.

We Are Proud To Be One of Their Suppliers

LAZARUS LABORATORIES

WEST CHEMICAL PRODUCTS LIMITED

_Rnother Fine Building Constructed | By — WILLIAMS, MURPHY & MacLEOD |

Pope Road Dial 436-9201

A

GEESE

sears

CO-OP

Charlottetown Departures: Frequency:

Flight No::

Equipment:

Depart: ‘

Frequency;

Flight No.>

e

aie Equipment

Depart:

Spring 1966 (Effective April 24, 1966)

1:30 p.m. for. Magdalen Islands

MARITIMES LOCAL SERVICES

fas? and Southbound Flights

Daily Except Gutiday

BC3

1:00 p.m. for New Glasgow and Halifax

Jaboratoris. that have gradually |. meni : : al : } seks is aiming at two. markets accumulated the evidence that! vaNCOUVER (CP)—A Los|here and in Seattle in an at-| “There is the sophisticated . TRI ELECTRIC CO i All. these lines of Pitch Angeles firm has set. up an of-|tempt to convince the smaller |computer customer who has : a converge on the “same mecha. fee nece- it an attempt. to_con- |business. firm to use the com> |data processing facilities but | 197 west La Moncton, .N.B. | gism that helps you eventually |Vince the small businessman to | puter. who is not getting access to a ne 0! : . Fecover from a cold, or permits | °on , ee sais ia Can does not pur- iad tone wen @ @ vaccination against a virus, or Sand : | . : prevents a patient from borrow- ; ie ; ok ~-{ng-a kidney: from ny Maamiogael “ Gann by a nau s Sor when his own .goes bad. government | » Indeed, “this area of cancef | Atomic eee OF ae = : i sa fesearch is closely tied to the | ] barrier that prevents individ. | “Quand, West. cs Carp. has | EASTERN PROVINCIAL AIRWAYS uals from exchanging organs in |the contract to operate the 1107

"EASTERN PROVINGIAL AIRWAYS

serving the Atlantic region

~

_ Daily

DBC

8:00 am for Magdalen .slands

West end Nerthbound Flights

Daily Except Saturday

Su

erside and

Daily Daily, Except.

. Sunday

DC-3

o

4:00 p.m tor 10:20

Summerside and

Except Sunday

ne-3

as general contractors on this fine new

building,we wish the management and “__ staff of Agro Co-op afl the best in their future business endeavours.

shee

congratulates

Sunday :

SS

DC-38

a.m. for 10:45 a.m. for

, & Summerside and Summerside and

- 31,.1964, Americans bought 46,- Investigation.” Moncton Moncton Moncton Moncton 80 acres in the survey area “A frequent response was that Y *h This net {nerease brought: land in the area: had been un. vee

-American-owned land to a total dervalued “of 281,120 acres in the strip of $8,114,741 acres:

in economic terms nd American buyers -had rec- | ognized it as a good invert.

Mr, McFarlane saidi ‘ment.’

ih

Class One Service. AN times are local Hmes. For information of connecting service with Newfoundland v la

Labrador, consult your lodal EPA ticket agent:

™ /

AGRO CO-OPERATIVE LTD.

ASSOCIATION on the

opening of their

‘modern

FARM SUPPLY CENTRE.

Exhibition Drive CHARLOTTETOWN, P.E.I.:

Agro Co-operative is a supplier of Cyanamid Animal Feed and Halth Products, including:

AUREO C.P.-250

\

CYANAMID OF CANADA LIMITED

635 Dorchester Blvd. W. _ Montreal 2: Quebec